Senior Principal Scientist, Agentic Systems Development for Drug Discovery Job at Vertex Pharmaceuticals, Boston, MA

  • Vertex Pharmaceuticals
  • Boston, MA

Job Description

Vertex Pharmaceuticals seeks a Senior Principal Scientist to develop and deploy agentic AI systems for drug discovery. The role combines computational expertise with scientific leadership to create AI-enabled workflows that enhance small molecule and protein therapeutic discovery, requiring strong cheminformatics and software engineering capabilities.

Responsibilities

  • Translate scientific requirements into autonomous agentic AI solutions for drug discovery
  • Build, test, and deploy AI-enabled scientific workflows across small molecule and protein therapeutics
  • Design testing, evaluation, and validation strategies for agentic AI systems
  • Collaborate with computational scientists, engineers, and research teams on scalable AI solutions
  • Stay current with emerging agentic AI patterns and prototype new scientific capabilities

Requirements

  • Ph.D. in Computational Chemistry, Cheminformatics, or related scientific discipline
  • 8+ years experience in scientific software development applied to drug discovery
  • Expert knowledge of small molecule computational methods and cheminformatics
  • Hands-on experience developing, deploying, and managing AI-enabled scientific products
  • Strong Python skills and production-grade software development capabilities
  • Deep understanding of agentic AI systems, LLMs, and modern AI technologies
  • Experience translating scientific requirements into scalable computational solutions

Compensation: $168,000 - $252,000 base

Job Tags

Similar Jobs

Villa Hope

2nd and 3rd shift Residential assistant Job at Villa Hope

 ...difference in the lives of others and in your community!$1000 Sign-On Bonus!! Villa Hope is hiring Residential Assistants for all shifts. If your passion is to help those in need, we feel that we have a position for you! Our focus is on caring for our residents... 

MDD Forensic Accountants

Senior Allocation Analyst - Remote Forensic Analytics Job at MDD Forensic Accountants

A leading forensic accounting firm is seeking a Senior Allocation Analyst to support their forensics team. This role involves building claim-level allocation models, performing quantitative analysis on complex insurance claims, and providing clear communications to stakeholders... 

TravelNurseSource

Travel Nurse RN - Progressive Care Unit - $2,311 per week in Anchorage, AK Job at TravelNurseSource

 ...Registered Nurse (RN) | Progressive Care Unit Location: Anchorage, AK Agency: Lancesoft Inc Pay: $2,311 per week Shift Information: Days - 3 days x 12 hours Contract Duration: 13 Weeks Start Date: 10/19/2026 About the Position TravelNurseSource... 

Auto-Owners Insurance Group

Entry Level Underwriter Job at Auto-Owners Insurance Group

 ...specific role could have the flexibility to work from home up to 3 days per week. Auto-Owners Insurance, a top-rated insurance carrier, is seeking a motivated underwriting trainee to join our team. This job performs and applies insurance coverage, rules and guidelines... 

Cynet Health

Travel Physical Therapy Assistant (PTA) - $1,552 per week in Westfield, NJ Job at Cynet Health

 ...Contract Duration: 13 Weeks Start Date: 7/20/2026 About the Position Job Title: Patient Transport Assistant Profession: PTA Specialty: 3043 Duration: 13 weeks Shift: 08:30 - 16:30 Hours per Shift: 8 Experience: Minimum years of experience required...